Research Article
Cortical Gray Matter Thickness to Pons Ratio: A Novel Diagnostic Index for Alzheimer’s Disease
Issue:
Volume 9, Issue 1, February 2024
Pages:
1-7
Received:
4 October 2023
Accepted:
20 October 2023
Published:
8 January 2024
Abstract: Introduction: Alzheimer’s disease is a chronic neurodegenerative disease that is being diagnosed more and more commonly in neurology clinics. Physicians are familiar to see brain atrophy definition in the MRI reports of these patients. To aid physicians in the diagnosis, we aimed to find a novel radiological diagnostic index for Alzheimer’s disease by making MRI-based specific measurements. Materials and Methods: Fifty-three patients diagnosed with typical Alzheimer’s disease and fifty-five healthy control cases were enrolled in our study. Demographic data containing age, gender, and medical history were recorded. Non-contrast 1.5T brain magnetic resonance images of all participants were collected. Measurements of the prefrontal and precentral sulcus cortical gray matter thickness, as well as the area of the pons, were done by a radiologist. The cortical thickness to the pontine area ratio was calculated and compared between the two groups. Finally, a ROC curve analysis was done to find a certain index value. Results: In the patient group, prefrontal and precentral gray matter thicknesses were significantly lower than in the control group. Also, the ROC curve analysis revealed a crucial ratio of prefrontal gray matter thickness to the pontine area. This novel radiological index ratio distinguished Alzheimer's disease atrophy from healthy variances with a sensitivity of 21% and a specificity of 97%. Conclusion: The radiological ratios that we found in our study can not be caught by the human eye. Calculating and reporting our suggested index ratio in brain MRI reports may provide additional information for physicians diagnosing Alzheimer's disease.
Abstract: Introduction: Alzheimer’s disease is a chronic neurodegenerative disease that is being diagnosed more and more commonly in neurology clinics. Physicians are familiar to see brain atrophy definition in the MRI reports of these patients. To aid physicians in the diagnosis, we aimed to find a novel radiological diagnostic index for Alzheimer’s disease...
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Research Article
Family Climate and Personal Resilience Among Children Victims of Sexual Abuse in Abidjan
Inoussa Daboné*,
Ettié Silvie Kouassi,
Aminata Haïdara*
Issue:
Volume 9, Issue 1, February 2024
Pages:
8-13
Received:
31 December 2023
Accepted:
15 January 2024
Published:
21 February 2024
Abstract: In Ivory Coast, the proportion of children victims of sexual abuse has become increasingly worrying since the post electoral crisis of 2011. This study aims to analyze the effect of family climate on the personal resilience construction of children victims of sexual abuse. It is so based on the working hypothesis that children victims of sexual abuse who benefit from a supportive family climate are more resilient than those who evolve in a non-supportive family climate. The study was conducted following a qualitative methodological approach with a descriptive aim, with 22 children of both sexes, victims of sexual abuse and aged from 06 to 13 years old. These children were selected by a reasoned choice at the Infant Guidance Center of Abidjan. They were subjected to a semi-structured interview from May 09 to August 10, 2022. The results, interpreted in the light of the theory of attachment, indicate that the family climate is decisive in the construction of personal resilience in children victims of sexual abuse. These results show the importance of raising awareness about the children sexual abuse and the need to provide support to the families of sexually abused children with a view to strengthening their capacity of resilience when facing such a serious phenomenon.
Abstract: In Ivory Coast, the proportion of children victims of sexual abuse has become increasingly worrying since the post electoral crisis of 2011. This study aims to analyze the effect of family climate on the personal resilience construction of children victims of sexual abuse. It is so based on the working hypothesis that children victims of sexual abu...
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